This study examines the semantic relations between lexical units in dan, a mande language spoken in Côte d’Ivoire, focusing on synonymy, antonymy, meronymy-holonymy, metonymy, ambiguity, polysemy and homonymy. Grounded in lexical semantics and cognitive linguistics, the research combines a descriptive and interpretative approach based on examples inspired by authentic dan usage. The analysis shows that the dan lexicon is organized through complex relational networks in which part-whole relations and metonymic transfers play a central role. Meronymy appears as a structural principle reflecting cultural categorizations of the body, while metonymy operates as a dynamic mechanism of meaning construction in discourse. The study of semantic ambiguity highlights the flexibility of lexical interpretation and the predominance of motivated polysemy over strict homonymy. These findings contribute to a better understanding of meaning organization in dan and provide methodological tools for further lexicographic and comparative research within the Mande linguistic area.